The article of the week is a recently published systematic review looking at the sensitivity/specificity of RADT in kids/adults with suspected GABHS Pharyngitis.
The data from the 59 studies (55K patients) is impressive and may be helpful in determining who should get cultured, antibiotics, or nothing at all.
I’ve also included a link the most recent AHA/AAP guidelines for the assessment and management of GABHS.
1. Stewart EH, Davis B, Clemans-Taylor BL, Littenberg B, Estrada CA, Centor RM. Rapid antigen group A streptococcus test to diagnose pharyngitis: a systematic review and meta-analysis. PLoS One. 2014 Nov 4;9(11):e111727. doi: 10.1371/journal.pone.0111727. eCollection 2014.
2. Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA. Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation. 2009 Mar 24;119(11):1541-51. doi: 10.1161/CIRCULATIONAHA.109.191959. Epub 2009 Feb 26.